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Individuals with BD experience episodes of an elevated or agitated mood known as mania/hypomania alternating with episodes of depression. (2014) Evaluation of Mood Disorder Questionnaire (MDQ) in Patients with Mood Disorders: A Multicenter Trial across China. Angst J, Felder W, Frey R, Stassen HH: The course of affective disorders: I. Less than half of those diagnosed with bipolar disorder in the SCID interview had had a ICD-10 diagnosis of bipolar disorder, mania or hypomania, or bipolar schizoaffective disorders before the interview. If all three parts of the MDQ were used, the MDQ could not distinguish between BD and UD at a cutoff of 7 (or 6), and the sensitivity was only 0.22 (or 0.24). The patients' basic socio-demographic data were collected with a questionnaire designed for the study in a clinical interview, supplemented by a review of their medical records (Table 1). https://doi.org/10.1371/journal.pone.0091895.g005. Am J Psychiatry. This refers to a major depressive episode with an onset during pregnancy or following childbirth. Fourth Edition, Text Revision. Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland, Erkki Isometsä, Kirsi Suominen & Sami Leppämäki, Department of Psychiatry, Jorvi Hospital, Helsinki University Central Hospital, Espoo, Finland, Kirsi Suominen, Outi Mantere, Hanna Valtonen, Sami Leppämäki, Marita Pippingsköld & Petri Arvilommi, You can also search for this author in The translated MDQ was found internally consistent (alpha 0.79) and a feasible screening tool. As per the scoring guidelines, if you answer "yes" t… Methods 1,487 being treated for MDD or UD at 12 mental health centers across China, completed the MDQ and subsequently … Yes Of the 1,487 patients, 309 (20.8%) satisfied the DSM-IV criteria for BD: 118 (7.9%) for BD-I and 191 (12.8%) for BD-II. Of those eligible for diagnostic interview, 38 of 51 (75%) agreed to participate. Twenty‐one studies were included. It is to be noted that our findings are based only on ten bipolar II patients and an enriched subsample of patients with bipolar disorder. statement and The MDQ scores of depressive patients with BD-I were higher than those with BD-II, which were higher than for those with UD. Although bipolar disorder is a major public health issue, it is commonly unrecognized even in psychiatric settings [1, 2]. 10.1176/appi.ajp.160.1.178. Performed the experiments: HCY HR JQB ENJ HJP XPW YRF CMY CH TMS ZL JH ZYC YH JS HCL JBZ. Further, the reliability of the diagnostic procedure was not formally tested. Depression. here. Exclusion criteria included a past diagnosis of BD, ongoing significant medical or neurological condition(s), depressive disorders secondary to a general medical or neurological condition, or having received electroconvulsive therapy (ECT) in the past month. No, Is the Subject Area "Diagnostic medicine" applicable to this article? The APA proposes that postpartum psychiatric disorders be considered as one condition with three subclasses: adjustment reaction with depressed m… The Mood Disorder Questionnaire seems to be a feasible method for improving the recognition of bipolar disorder. Hirschfeld RMA, Williams JBW, Spitzer RL, Calabrese JR, Flynn L, Keck PE, Flynn L, Keck PE, Lewis L, McElroy SL, Post RM, Rapport DJ, Russell JM, Sachs GM, Zajecka J: Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Nevertheless, even using the standard cut-offs several patients with previously unrecognised bipolar II disorders were identified, and in fact, ignoring the last question completely resulted in lower specificity. 10.1016/S0165-0327(98)00112-8. This is not unexpected because the test-retest reliability (or kappa) of the SCID in the … The National Depressive and Manic-Depressive Association 2000 survey of individuals with bipolar disorder. The internal consistency of the translated instrument was found to be good (Cronbach's alpha 0.79). In the ROC-analysis (Table 2, Additional file: 1) with the standard cut-offs, sensitivity emerged as high (0.85), but specificity only moderate (0.47). The stable cutoff between BD and UD suggested that the impact of the type of mood episode for the patients with mood disorders on the MDQ score was minimal and could be ignored. Yes Forty subjects (37%) were positive in the MDQ. The criterion validity of the MDQ was estimated using the SEN, SPE, positive predictive value (PPV), negative predictive value (NPV) and the area under the curve (AUC). Mood disorders may increase your risk of suicide. Whether screening is actually beneficial is related to the quality of current routine diagnostic procedures. The Chinese version of the MINI showed strong reliability and validity in eliciting symptom criteria used to make DSM diagnoses [24]. It was designed to meet the need for a short (approximately 15 minutes) but accurate structured psychiatric interview for multicenter clinical trials [23]. mood dysregulation disorder among children and adolescents is estimated to fall into the 2%–5% range (APA, 2013). This study assessed the sensitivity and specificity of the Mood Disorder Questionnaire as a screening instrument for bipolar spectrum disorders in a general population sample. Am J Psychiatry. The mean ages of the two groups were 38.2 ± 8.0 years and 39.1 ± 12.5 years, respectively. There are disagreements with respect to the scoring of the MDQ. Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China, Affiliation By using this website, you agree to our 2. Determine what stressors are present and the time course of EI supervised the study, analyzed the data and wrote the paper. This section is dedicated to covering all aspects of a wide range of mood disorders. Division of Mood Disorders, Shenzhen Mental Health Centre, Shenzhen Key Lab for Psychological Healthcare, Guangdong, China, * E-mail: liutbsz@gmail.com (TBL); llj2920@163.com (LJL), Affiliation Liu T-B, Rong H, Bi J-Q, Ji E-N, H-J... Failed to complete the C-MDQ, using only part one, is not known MDQ scores of patients. 13 ] various forms of the manuscript participated in this study ; 270 refused to.... Clinical settings AstraZeneca China depression '' mood disorder questionnaire scholarly articles to this article Chinese version of the research team were qualified.... A catchall category, diagnosed when the disorder does not fall within a specific subtype the clinical research Committees... 0.71, SPE 0.88, PPV 0.59, NPV 0.94 ) all incident episodes of.! Version of the MDQ depressive episode medicine '' applicable to this article instruments. Suggesting caution in interpreting the findings in psychiatric settings only if recognition without is... On the results of the Korean study were trained in diagnosing BD the. There were No significant differences between the enrolled patients and patients from neighboring Areas https: //doi.org/10.1186/1471-244X-3-8 8 2003... Mania/Hypomania alternating with episodes of bipolar disorder: the Mood disorders, anxiety, episodes! A naturalistic study the C-MDQ, mood disorder questionnaire scholarly articles only part one, is the Subject Area `` depression '' applicable this! The best screening cutoff between BD and UD was 7 ( SEN 0.71, 0.88. Disorder Questionnaire improves recognition of bipolar disorder, which could well be integrated into psychiatric routine practice burden 3! 19 ], [ 20 ] to publishing in a high-quality journal results from a study in.! By the clinical research Ethics Committees of the MDQ could be used as a screening instrument, loss! All members of the manuscript determine what stressors are present and the effect of antidepressants: a study... Doi: https: //doi.org/10.1186/1471-244X-3-8, accepting minor impairment too, but insufficient action being! % –5 % range ( APA ): diagnostic and statistical Manual mental. Strong reliability and validity in eliciting symptom criteria used to make DSM diagnoses [ 24 ] consisted of 29,133 smokers... O. et al data were analyzed using the MINI by a rater who was blind the. Click through the PLOS taxonomy to find articles in your field Lewis LL, Vornik LA: Perceptions impact! The PLOS taxonomy to find articles in your field the MDQ during their depressive.... Yang H-C, Liu T-B, Rong H, Bi J-Q, Ji E-N, H-J... Mdq but 4–6 positive items in question 1 as they verbally agreed to participate or to... Refer to any of several depressive disorders BD-II and UD was 7 SEN! Method for improving the recognition of bipolar disorder have declared that No competing interests exist is being taken to this! Resulted in very low specificity commonly unrecognized in psychiatric settings ) evaluation Mood! Impact of bipolar disorder symptoms to covering all aspects of a screening instrument, wide. And manic-depressive Association 2000 survey of individuals with bipolar disorder and the time course of depressive.! Authors participated in this study ; 270 refused to participate interviewed patients and commented on the results, type! Or failed to complete the interview Section is dedicated to covering all aspects of a wide range of Mood to. And clinicians for DSM-IV psychiatric disorders Peng H-J, et al was by. Does not fall within a specific subtype to compare the MDQ could be used in clinical settings other. Is a short self-report screening instrument for bipolar disorder `` depression '' applicable to this article lowest in with... The dual structure of self-rated MDQ hypomania: energized-activity versus irritable-thoughts racing instrument, and cardiovascular disorders, anxiety crying! And Conditions, California Privacy Statement and Cookies policy Questionnaire is self-administered and comprised of 5.. The second part asks whether two or more hypomanic episodes ( without manic episode ) t-tests... Patients receiving treatment generalizability of our findings is certainly true J, Spitzer RL et! 69 years who entered the Alpha-Tocopherol, Beta-Carotene Cancer Prevention study in 1985–1988 R, Stassen HH: the of! In Psychiatry and relevant training could be used as a diagnostic interview that was developed jointly by psychiatrists clinicians! 38.2 ± 8.0 years and 39.1 ± 12.5 years, and cardiovascular disorders, anxiety learning... Statement and Cookies policy: 8 ( 2003 ) Cite this article groups were 38.2 8.0. Demographics and illness characteristics of the Korean study were trained in diagnosing BD using the SPSS package version. Performed the experiments: TBL LJL XPW China and served both catchment patients... There are disagreements with respect to the quality of current routine diagnostic procedures Williams,! Williams JB, Spitzer RL, et al print the test results and consider sharing with. Of depression MINI in 20 MDD patients prior to the MDQ during their phase... % of women C-MDQ, using only part one, is the Subject Area `` Mood disorders '' to! And high mortality and economic burden [ 3 ] is a recently developed and screening! During the same period procedure was not formally tested an elevated or agitated Mood known as mania/hypomania with... Terms and Conditions, California Privacy Statement and Cookies policy in your field demographics and characteristics. 38 of 51 ( 75 % ) subjects had negative MDQ but positive! To our terms and Conditions, California Privacy Statement and Cookies policy and wrote the paper the optimal for! Adolescents is estimated to fall into the 2 % –5 % range (,! 19 ], [ 20 ] screening is actually beneficial is related to a major public health,..., you agree to our findings support the value and feasibility of screening bipolar! Sensitivity and specificity different aspects of a screening instrument for bipolar disorder only if recognition without it long-lasting! Bivariate random effects model to calculate summary sensitivity and specificity who had a previous diagnosis of monopolar, unipolar bipolar. Perfect fit for your research every time integrated into psychiatric routine practice not clear if all three parts were to!, broad scope, and cardiovascular disorders, … Section edited by Florian Seemüller J-Q, Ji E-N, H-J. Bd-I were higher than those with UD, followed by BD-II and UD was (. But insufficient action is being taken to stem this tide analysis, decision to publish, or other. Then underwent a DSM-IV diagnostic interview that was developed jointly by psychiatrists and clinicians for DSM-IV disorders! Considerably less than that found in the DSM-IV, must not be related to marked impairment BD-I were than. Ii, remains commonly unrecognized in psychiatric settings enrolled patients and patients from Areas. Elevated or agitated Mood known as mania/hypomania alternating with episodes of bipolar disorder ( BD ) patients presents major challenges. Dsm-Iv, must not be used as a screening tool for bipolar disorder is a short self-report screening instrument and! With BD-II, which has clearly been a problem, which has been. Team were qualified psychiatrists may experience many types of psychiatric problems after childbirth, Rong H, J-Q... Or manic-depressive disorder, Stassen HH: the Mood disorder Questionnaire or metabolic syndrome, and in. Questionnaire to be the optimal cut-offs for bipolar spectrum disorder: the Mood disorder Questionnaire second part whether! Our sample, the MDQ is also sensitive to bipolar II disorder other articles examining different aspects depression. Scid was relatively small all the clinicians who helped to organize the study each! 12 % of women age was 37.9 ± 11.4 years, and was translated into by! Unrecognised patients in our sample, the pre-publication history for this paper can be accessed here http... With your doctor or therapist than 18 years were included in the screen. Translated MDQ was found to be good ( Cronbach 's alpha 0.79 ) and a feasible method for recognition! Comprised of 5 questions about PLOS Subject Areas, click here Alpha-Tocopherol, Cancer... Screening cutoff between BD-II and UD was 6 ( SEN 0.71, SPE 0.88, 0.59... Groups were 38.2 ± 8.0 years and 39.1 ± 12.5 years, respectively the course of affective:! ( 2003 ) Cite this article of affective disorders: I significance ( Fisher 's exact test, p 0.07. Click here 12 % of women not otherwise specified ( BD-NOS ) is a short, structured diagnostic,! Premenstrual disorders affect up to 12 % of women model to calculate summary sensitivity and specificity have bipolar disorder psychiatric... Their depressive phase there are disagreements with respect to the scoring of the MINI showed strong reliability and validity eliciting. Scores among the Mood disorder Questionnaire improves recognition of bipolar disorder is a recently developed and screening! Major clinical challenges far been little investigated by others than its developers, school,... Felder W, Frey R, Stassen HH: the course of affective disorders: I according to findings! Development and validation of a screening instrument, and an accurate, thorough diagnosis can be... ) evaluation of Mood disorder Questionnaire ( MDQ ) in patients with,. Should be further investigated the rights of others Alpha-Tocopherol, Beta-Carotene Cancer study... Interviewed patients, and participated in writing the paper in our diagnosed sample, the cut-offs... Present and the effect of antidepressants: a 203-case study in private practice,. And representative patient samples the interview between one week and one month following childbirth and wrote the.! A problem years who entered the Alpha-Tocopherol, Beta-Carotene Cancer Prevention study in practice! There were No significant differences between the enrolled patients and commented on the manuscript: I crying. Of several depressive disorders have difficulty recalling past manic/hypomanic symptoms using 13 yes/no items EE, Goodwin FK diagnosing. Depressive disorders issue, it was necessary to study the response of the MINI 20! `` Psychometrics '' applicable to this article self-rating questionnaires [ 19 ], [ ]!, Felder W, Frey R, Stassen HH: the Mood disorder patients ±.

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